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Heres what you can generally expect from semaglutide treatment: Injection site: The injection is usually given in the abdomen, thigh, or upper arm

This broad regulatory activity includes upregulation of tissue repair genes, collagen synthesis pathways, antioxidant defense systems, and anti-inflammatory signaling networks, alongside simultaneous downregulation of genes associated with tissue destruction, inflammation, and fibrosis

however, senescent cells infamously secrete high levels of pro-inflammatory cytokines, chemokines, and extracellular matrix-degrading proteins that negatively impact the extracellular environment and induce spread of senescence to non-senescent cells (29-32)

High levels of this chemokine can upregulate nicotinamide adenine dinucleotide phosphate-oxidase 1 (NOX1) in glial cells, triggering the production of reactive oxygen species (ROS) and potentiating glutamate-induced neuronal death 29